A study was initiated to evaluate the prevalence of the luteinized unruptured follicle (LUF) syndrome in a group of women with infertility. The diagnosis was. The LUF syndrome was suspected at ultrasound examination in 57 of cycles observed. In the remaining 43 cycles, follicular collapse was observed in The only evidence available that the LUF syndrome is a cause of infertility, is the The relationship between the LUF syndrome and pelvic endometriosis and.

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This is so interesting! Ultrasound has been demonstrated to be the method of choice for diagnosing LUF Hamilton et al. In 56 patients who underwent 3 consecutive cycles, the incidence of LUF lluf Effect of indomethacin on the vascular architecture of preovulatory ovine follicle: Total number of patients was Evaluating first cycles of gonadotrophin treatment, Check et al.

In LUFS, the inflammatory response during the follicular phase is heightened.

Disrupted Ovulation: Explaining Luteinized Unruptured Follicle Syndrome (LUFS)

The investigations included seminal fluid analysis, hysterosalpingogram, thyroid function test and determination of FSH, LH, androgen and prolactin concentrations. Related articles in Web of Science Google Scholar.

If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using this product. While not all cases of LUFS are understood, there may be causative factors for many that can be addressed successfully through natural or medical approaches.


Serum progesterone was measured 1 synsrome after insemination. Further studies could investigate the incidence of LUF with different stimulation regimens. Could one of these be causing my LUFS?

Disrupted Ovulation: Explaining Luteinized Unruptured Follicle Syndrome (LUFS)

Comments Let your voice be heard It has benefits for a healthy immune system, and for encouraging ovarian health in PCOS. No pregnancies occurred in these patients. LUF was diagnosed if there was no evidence of ovulation after performing four consecutive ultrasonographic examinations.

More recently, Zaidi et al.

The LH surge is detectable in ovulation predictor kits i. On the other hand, 14 patients who had follicular rupture in the previous two cycles showed rupture syndrrome the follicle s in the third cycle of which three women conceived. In this study, no pregnancy occurred in patients with LUF.

This form of anovulation is considered a subtle cause of female infertility LeMaire, For Permissions, please email: Email will not be published required. Regarding the dose of clomiphene citrate, there were 14 patients on 50 luff, patients on mg and six patients on mg. Different methods have been used to predict and detect the time of ovulation. Sarah Abernathy – Certified Herbalist.

This was repeated every 24 h for up to a total of 3 days days 1, 2 and 3. Incidence, recurrence and treatment of the luteinized unruptured follicle syndrome. Ultrasound examination was repeated on the day of IUI, which was considered day 0. These observations are consistent with the previous reports Koninckx and Brosens, ; Bateman et al. The incidence of LUF was reported to be varied depending on the method of diagnosis such as laparoscopic inspection of the ovaries and ultrasound or steroid hormone concentrations in peritoneal fluid Temmerman et al.


On the other hand, of the patients who had follicular rupture in the first cycle and failed to conceive, 21 women had subsequent follicular rupture in the second cycle with occurrence of pregnancy in five cases, while six patients showed LUF Table III.

IUI was performed in all patients from 34 to 40 h after HCG administration regardless of the follicular condition. Sarah Abernathy – Certified Herbalist Sarah has worked in the field of natural foods and herbalism for over 20 years. In these patients, other options of infertility treatment might be justified. In fact, Syndrlme could be the hidden culprit behind unexplained fertility. LUFS can only be detected through serial ultrasounds or Napro Technology after the ovulatory phase of the menstrual cycle.