Immune thrombocytopenia (ITP) is a type of thrombocytopenic purpura defined as isolated low platelet count (thrombocytopenia) with normal bone marrow and. Idiopathic thrombocytopenic purpura (ITP) is defined as a hematologic disorder, characterized by isolated thrombocytopenia without a clinically apparent cause. Eur J Haematol Suppl. Mar;(71) doi: /j x. Immune thrombocytopenic purpura: epidemiology and implications for.

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National Center for Biotechnology PurpursU. Allergic contact dermatitis Mantoux test. It is recommended that pregnant women with thrombocytopenia or a previous diagnosis of ITP should be tested for serum antiplatelet antibodies.

Idiopathic thrombocytopenic purpura

This increased risk of death with ITP is largely concentrated in the middle-aged and elderly. In chronic refractory cases, where immune pathogenesis has been confirmed, [15] the off-label use of the vinca alkaloid [16] [17] [18] and chemotherapy agent vincristine may be attempted. She suffered from prupura gums with the appearance of tromboditopeni purple spots all over the body, bleeding into the right eye and melena since last 10 days.

A report of 66 cases. Helicobacter pylori and idiopathic thrombocytopenic purpura.

The platelet count of the patient was monitored every fortnight and was found to be normal after completion of one-week anti- H. Many older recommendations suggested a certain platelet count threshold usually somewhere below However, the use of bleeding time in diagnosis is discouraged by the American Society of Hematology practice guidelines [10] and a normal bleeding time does not exclude a platelet disorder.


Treatment should be restricted to those patients with moderate or severe thrombocytopenia who are bleeding or at risk of bleeding. The exact mechanism by which dapsone assists in ITP is unclear. For patient with active H. Ninety-six percent of prupura ITP-related deaths were individuals 45 years or older. Journal List Gastroenterology Res v.

Bleeding time from minor lacerations or abrasions is usually prolonged. At least 70 percent of childhood cases will end up purputa remission within six trombositoleni, even without treatment.

Werlhof, is characterized by premature destruction of autoantibody-coated platelets [ 1 ], causing thrombocytopenia and subsequent mucocutaneous bleeding. Platelet transfusions may be used in severe bleeding together with a very low count. Intravenous immunoglobulin IVIg may be infused in pyrpura cases in order to decrease the rate at which macrophages consume antibody -tagged platelets.

Patients with mild, asymptomatic thrombocytopenia, discovered incidentally on a routine blood count, should not be treated. Idiopathic thrombocytopenic purpura ITP is defined as a hematologic disorder, characterized by isolated thrombocytopenia without a clinically apparent cause.

The diagnosis of ITP is a process of exclusion.

Splenectomy removal of the spleen may be considered in patients who are either unresponsive tombositopeni steroid treatment, have frequent relapses, or cannot be tapered off steroids after a few months. Hence one may be considered thrombocytopenic below that range, although the threshold for a diagnosis of ITP is not tied to any specific number. It should be limited in duration unless demonstrated that symptomatic thrombocytopenia persists. From traditional medicines to modern drugs.


Then, secondary causes 5—10 percent of suspected ITP cases should be excluded. The prevalence of Helicobacter pylori infection and the effect of its eradication were monitored in an ITP patient over a period of 12 months.

It is recommended that neonates be followed with serial platelet counts for the first few days after birth. Idiopathic thrombocytopenic purpura ITP is an immune-mediated thrombocytopenia. Archived from the original on The patient was followed-up for 2 years and there was no re-occurence reported.

Immune thrombocytopenic purpura: epidemiology and implications for patients.

Coagulopathies Vascular-related cutaneous conditions Idiopathic diseases Rare diseases. Open in a separate window. Such secondary causes include leukemiamedications e. The evolution of drug discovery: It is a thrombopoiesis stimulating Fc-peptide fusion protein peptibody.

Introduction Idiopathic thrombocytopenic purpura ITP is the condition of having a low platelet count thrombocytopenia of no known cause idiopathic. On examination of the trombositkpeni marrow, an increase in the production of megakaryotes is seen and can help in determining ITP. British Journal of Haematology. Infobox medical condition new All articles lacking reliable references Articles lacking reliable references from July Children should be discouraged idikpatik rough contact sports or other activities that increase the risk of trauma.