Fournier’s gangrene, an obliterative endarteritis of the subcutaneous arteries resulting in gangrene of the overlying skin, is a rare but severe infective necrotizing. Profile of patients with Fournier’s gangrene and their clinical evolution. Perfil dos pacientes com gangrena de Fournier e sua evolução clínica. DJONEY RAFAEL. La gangrena de Fournier es una infección grave de la zona genital de los ciertas afecciones corren un mayor riesgo de llegar a tener gangrena de Fournier.

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Contemporary diagnosis and management of Fournier’s gangrene

The primary goal of reconstruction in patients who have undergone genital skin loss due to necrotizing fasciitis is simple and efficient coverage.

Moreover, the flap was found to be less bulky than a gracilis flap with minimal donor site morbidity [ Chen et al. In contrast, anorectal sources of infection usually start in the perianal area, a clinical variation that can serve as a guide to localizing the foci of infection [ Smith et al.

Cent Eur J Urol Similar to other necrotizing soft tissue infections, the inflammation and edema from the polymicrobial infection lead to an obliterative endarteritis of the subcutaneous arteries [ Korkut et al. The diagnosis of FG is primarily clinical, and in most cases imaging is neither necessary nor desirable. In their study of 44 patients presenting with FG, Ozturk and colleagues found that in 18 patients that required temporary stoma formation, significant increases in healthcare costs were observed without an effect on outcomes.

Etiology FG was initially defined as an idiopathic entity, but recent research has shown that less than a quarter of FG cases are now considered idiopathic [ Smith et al.

SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal’s impact. It is imperative that the antibiotic regimen chosen is effective against staphylococcal, streptococcal and gram-negative bacteria, coliforms, Pseudomonas, Bacteroides and Clostridium [ Mallikarjuna et al.

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All the patients were men, In addition to demonstrating significant swelling of the scrotal soft tissue, radiographs may also detect subcutaneous emphysema extending from the scrotum and perineum to the inguinal regions, anterior abdominal wall and thighs.

However, involvement of the testis suggests retroperitoneal origin or spread of infection [ Eke, ; Chawla et al. In a retrospective review of 41 patients presenting with FG, Chen and colleagues found that scrotal advancement flaps provided good skin quality and cosmesis in small to medium sized scrotal defects.

Contemporary diagnosis and management of Fournier’s gangrene

Conflict of interest statement: However, they are still clinically effective and successfully used in the management of large wounds [ Czymek et al. Predisposing factors Primarily an infective condition, FG has several predisposing factors and theoretically, any condition that decreases the host immunity may predispose a person to fiurnier development of FG.

The presence of severe sepsis on admission has been significantly associated with mortality [ Kara et al. Wound care was then subsequently performed for foyrnier next 2 weeks by the patient on an outpatient basis.

Fournier gangrene is associated with high mortality despite appropriate early treatment.

Singapore Med J Subscribe to our Newsletter. In patients infected with methicillin-resistant S. VAC therapy works by exposing a wound to subatmospheric pressure for an extended period to promote debridement and healing Figure 2 [ Mallikarjuna et al.

However, the association between larger gangrenous areas foudnier worse prognosis is not universally accepted [ Clayton et al. The common laboratory findings are nonspecific and may show anemia, leukocytosis, thrombocytopenia, electrolyte abnormalities, hyperglycemia, elevated serum creatinine level, azotemia and hypoalbuminemia gangrdna Shyam and Rapsang, ].

Moreover, it was found that mean number of surgical debridements in survivors was lower compared with that of nonsurvivors. Overall, Agngrena is considered superior to conventional radiography as soft tissue air is more obvious and scrotal contents along with Doppler blood flow can be examined. Meanwhile, patients with large and deep perineal defects often needed fiskopatologia myocutaneous or fasciocutaneous flap to eliminate dead space.


Although colostomy can be beneficial with regard to wound healing by avoiding fecal contamination, it should be performed only in selected cases because it increases morbidity. In cases of severe perineal involvement, colostomy has been used for fecal diversion or alternatively, the Flexi-Seal Fecal Management System can be utilized to prevent fecal contamination of the wound.

In 74 patients presenting with FG at an Egyptian medical center, adequate urinary diversion was accomplished with the use of a urethral Foley catheter in all but one patient who had experienced a urethral injury. Primarily an infective condition, FG has several predisposing factors and theoretically, any condition that decreases the host immunity may predispose a person to the development of FG.

Gangrena de Fournier | Cigna

The aerobic bacteria cause platelet aggregation and induce fieiopatologia fixation, thereby causing acceleration of coagulation. Czymek and colleagues prospectively collected data on 35 patients diagnosed with FG to assess the effectiveness of VAC therapy versus daily antiseptic polyhexadine dressings.

Am J Sur Open in a separate window. In a retrospective study of 19 patients diagnosed with FG, Chawla and colleagues studied the utilization of the FGSI to determine length of stay and survival.

Indications for suprapubic urinary diversion included patients with extensive penile and perineal debridement, or periurethral abscesses [ Hollabaugh et al. Tightness around the corona fisiopztologia base of the penis during erection was reported but was found to have resolved after 6 months.