PI & CMI Trade Names and Active Ingredients containing doxorubicin. 7 Documents available Doxorubicin Ebewe, PI, Doxorubicin hydrochloride. Doxorubicin. Doxil official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. Find information on drug affordability programs for DOXIL® (doxorubicin HCl liposome injection). Learn how patients who have been.
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TGA eBS – Product and Consumer Medicine Information
Respiratory, Thoracic and Mediastinal Disorders: Some patients may experience other side effects that doxxil not listed here. Advise females of reproductive potential of the potential risk to a fetus and to inform their healthcare provider with a known or suspected pregnancy [see Warnings and Precautions 5.
The risk of cardiomyopathy with doxorubicin HCl is generally proportional to the cumulative exposure.
Patients were stratified according to platinum sensitivity response to doxll platinum-based therapy and a progression-free interval of greater than 6 months off treatment and the presence of bulky disease tumor mass greater than 5 cm in size. Be sure to tell your doctor immediately if you experience any of these or other symptoms. Erythema, desquamation, or swelling interfering with, but not precluding normal physical activities; small blisters or ulcerations less than 2 cm in diameter.
Advise patients about the symptoms of infusion related reactions and to seek immediate doxkl attention if they develop any of these symptoms [see Warnings and Precautions 5. Body as a Whole.
Discontinue Doxil for burning or stinging sensation or other evidence indicating perivenous infiltration or extravasation.
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I have no coverage View all programs. Because clinical trials are conducted under widely varying conditions, the adverse reaction rates observed cannot be directly compared to rates on other clinical trials and may not reflect the rates observed in clinical practice.
Serious and sometimes life-threatening infusion-related reactions characterized by one or more of the following symptoms can occur with Doxil: For neuropathic pain or peripheral neuropathy, no dosage adjustments are required for Doxil.
Your doctor will monitor your heart function.
Los Angeles Cancer Network Doxil® – Los Angeles Cancer Network
This foundation provides financial assistance to those eligible for co-pays and travel costs associated with treatment. The information provided above on the drug you have selected is provided for your information only and is not a substitute for consultation with an appropriate medical doctor.
Clinical studies of Doxil conducted in patients with either epithelial ovarian cancer Trial 4 or with AIDS-related Kaposi’s sarcoma Trial 5 did not contain sufficient numbers of patients aged 65 and over to determine whether they respond differently from younger subjects. Ppi is also approved for the treatment of ovarian cancer that has stopped responding to platinum and paclitaxel-based chemotherapy regimens. Skin and subcutaneous tissue disorders: As with any printed reference, the use of particular drugs, regimens and drug dosages may become out-of-date over time, since new information may have been published and become generally accepted after the latest update to this printed information.
Please inform your doctor about your history of allergic ddoxil to medications or other substances. The use of the information on this site is subject to the terms of our Legal Notice and Pii Policy. Medically reviewed on Nov 1, Tell your doctor if you experience these or other side effects. If previous Grade 3 or 4 HFS: Secondary efficacy parameters were time to response, duration of response, and time to progression.
Two percent of patients developed signs and symptoms of congestive heart failure without documented evidence of cardiotoxicity. Please take me to the Healthcare Dozil site. We want to guide you to programs that may help.
Discontinue Doxil if no resolution after 2 weeks. The ultimate responsibility for patient care resides with a healthcare professional. The median time on study was 5.
Follow applicable special handling and disposal procedures.
Subscribe to receive email notifications whenever dodil articles are published. Advise pregnant women of the potential risk to a fetus. Call the programs or visit their websites to learn more. Of the 77 patients, 34 were evaluable for investigator assessment and 42 were evaluable for indicator lesion assessment; analyses of tumor responses are shown in Table The majority of infusion-related events occurred during the first infusion.