Isolation, Characterization and Evaluation of Anti-convulsant Activity of Rubus Antidiabetic Activity of the Plant Abutilon indicum in Streptozotocin Induced. Abutilon hirtum extract and fractions exhibited anti-inflammatory analgesic, antipyretic and antipyretic activities which may be attributed by the. Abutilon indicum Sweet is an Asia phytomedicine traditionally used to treat several disorders, including diabetes mellitus. However, molecular.

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The distribution region plays an important determinant of pine distribution and abundance in the landscape. This plant has a long history of being used medicinally as an antidiabetic remedy, and phytochemical screening of the plant revealed that it contained alkaloids, flavonoids, abtidiabetic, saponins and glycosides [ 1011 ].

Diabetes mellitus DM is a group activiyt metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both; the incidence of diabetes is increasing worldwide.

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Adiponectin is exclusively expressed by mature adipocytes and is the most abundant circulating adipokine. In this study, we investigated whether the extracts of A. This result will require confirmation such as measuring extracellular signal regulated kinases ERKswhich have been known to be responsible for the expression of GLUT1 [ 48 ].

Sweet is an Asian phytomedicine traditionally used to treat several disorders, including diabetes mellitus. The tribal community living in-the Melghat forest used abudlon indicum leaves to control diabetes mellitus.

Insulin resistance is a key feature in type 2 DM as well as in obesity and plays an important pathophysiological role [ 3 ]. The species suggests phytomedicine for anti-inflammatory, antimicrobial, antibacterial activities antidiabeticc industrial applications which are based on the antioxidant potential of the species.

The presence of narrow rectangular and thick walled epidermimal cells, trichomes and vascular bundles connected to the abaxial epidermis in the lamina, rosette cells, raphide, petioles actjvity wings etc. The results revealed that the use of leaves in controlling diabetes mellitus is justifiable. Thus, these data imply that the butanol fraction of A.

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To receive news and publication updates for Evidence-Based Complementary and Alternative Medicine, enter your email address in the box below. Dimethyl sulfoxide DMSO was used as vehicle control. Present investigation includes examination of morphological and microscopic characters, ash value, extractive values and Phytochemical evaluations including qualitative chemical examination of active constituents were carried out.

Enter your contact information below to receive full paper. Indexed in Science Citation Index Expanded. Pharmacognostical Studies of the Leaves of Cayratia carnosa Gagnep. The luciferase activity was expressed as a ratio of firefly to renilla luciferase activity. Traditionally the plant parts are used as sour, astringent and diuretic and is useful in conditions such vata, tumours, fever, neuralgia and splenopathy.

As there is no detailed on the standardisation work antidiabeticc on stem, the physicochemical parameters, brief study abutlon pharmacological activities xctivity microbial contamination analysis are carried out. Similarly petroleum ether extract and benzene extract were found to possess very good analgesic property.

Thailand and water ad libitum. Subsequently, we found that crude extract of A. Insulin resistance is characterized by a diminished reaction of insulin-sensitive tissues and a marked decrease in glucose metabolism in response to insulin. Subsequently, we examined the effect of the extract on transcription activation of GLUT1. The abhtilon glucose transport system may play an important role in the pathogenesis of peripheral insulin resistance, and glucose uptake in target tissues is a critical step in maintaining glucose homeostasis and in clearing the postprandial glucose load [ 45 ].

Pharmacognostical Evaluation of Tylophora indica Burm. Evidence-Based Complementary and Alternative Medicine. The results demonstrated abutilpn administration of A. However, traditional antidiabetic avtivity possess less adequate scientific or medicinal data support in spite of the fact that the World Health Organization still recommends further evaluation of their accepted use [ 89 ].

First, we observed the antidiabetic activity of aqueous extract of the entire plant leaves, twigs and roots of A.

View at Agutilon Scholar J. For pharmaceutical purposes, the quality of medicinal plant material must be high as that of other medicinal preparations.

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Results from other researchers have shown that this plant also contains saponins and glycosides [ 10 ]. Extracts of the roxburgii were tested for growth inhibitory against bacterial plant pathogens, mosquito. The needles being rich in resin content is a highly inflammable fuel for igniting forest fires.

A traditional belief regarding mode of administration of Asparagus racemosus AR says that Ksheerpaka milk decoction of Shatavari Asparagus racemosus is more potent as galactogogue than any other form of dosage. This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

In addition all the extracts have shown CNS depressant activity. By clicking on Request Paper you Agree to pay the above mentioned cost per paper.

Issue, Vol 20, Oct Suppl. As shown in Figure 5the extract enhanced glucose uptake in a concentration-dependent manner. Cost of Full Paper: The cells were washed twice with PBS and then assayed for luciferase activity as shown antidiabeticc. Binding Activity of A. In fact, it has been known that the extrapancreatic action of glibenclamide has an important role to inhibit glucose production by liver and improve carbohydrate metabolism in diabetes [ 3435 ], and increases glucose disposal by stabilizing GLUT1 protein at the plasma membrane of muscle [ 36 ].

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Volume2,Issue2 – Pharmacognosy Phytochemistry

The native Southeast Asian plant A. There exists a genetic predisposition to diabetes; however, environmental factors such as a sedentary lifestyle and obesity are the most prominent risk factors [ 2 activoty.

A similar significant decrease was also observed in rats treated with glibenclamide. Diabetes or activlty causes substantial morbidity, mortality and long-term complications, and remains an important risk factor for cardiovascular disease [ 1 ].